针灸联合基础药物治疗维吾尔族类风湿性关节炎的临床疗效观察

The clinical curative effect in combined use of acupuncture and medicine therapy in rheumatoid arthritis in Uyghur nationality

目的探讨针灸联合基础药物治疗维吾尔族类风湿性关节炎(RA)的临床疗效及安全性。方法将60例维吾尔族类风湿性关节炎患者随机分为观察组和对照组,每组30例,对照组采用基础药物治疗,包括口服甲氨蝶呤片7.5mg,1次/w、双氯芬酸纳缓释胶囊50mg,2次/d;观察组在药物治疗的基础上联合针灸治疗,均治疗1个疗程。对比两组临床疗效、临床症状改善情况、症状积分和视觉模拟评分(VAS)、血沉(ESR)和类风湿因子(RF)指标以及不良反应的发生情况。结果观察组总有效率(93.3%)显著高于对照组(73.3%),治疗后两组关节压痛数和晨僵时间均得到改善,观察组改善优于对照组;两组治疗后症状积分和VAS均较治疗前显著降低,观察组降低更显著;两组治疗后ESR和RF均较治疗前显著降低,两组治疗后比较差异无统计学意义;治疗期间两组均未见明显不良反应发生。结论针灸联合基础药物治疗维吾尔族类风湿性关节炎临床疗效确切、安全,能有效改善患者临床症状和中医症候,缓解疼痛。

Objective To investigate the clinical efficacy and safety of combined acupuncture and medicine therapy in rheumatoid arthritis （RA） in uygur race.Methods 60 cases of Uyghur patients with rheumatoid arthritis were randomly divided into observation group and control group,30 cases each.the Control group was treated with drug therapy, including oral Methotrexate Tablets 7.5 mg, 1/w, diclofenac sodium sustained release capsules 50 mg,2 times/d;while the observation group based on the combination of acupuncture and moxibustion treatment,was treated with a course of treatment;then we Compared clinical curative effect,clinical symptoms,symptom score and visual analogue scale （VAS）, erythrocyte sedimentation rate （ESR）and rheumatoid factor （RF）and adverse reaction of two groups.Re-sults Total effective rate of observation group is significantly higher than the control group,the clinical symptoms of two groups were improved,the observation group was better than the control group;the two group of symptom score and VAS were significantly reduced,the observation group decreased more signif-icantly;two groups of ESR and RF decreased significantly at the end of treatment,compare the differences between the two groups after the treatment without statistical significance;the two groups were no obvious adverse reactions during treatment.Conclusion Acupuncture and drug therapy in rheumatoid ar-thritis are safety,and can improve the clinical symptoms and TCM symptoms effectively.