基于因子分析的轻度认知障碍中医证候要素研究

Study On Syndrome Elements of Mild Cognitive Impairment Based on Factor Analysis

目的:探讨轻度认知障碍的证候要素,为该病的辨证论治提供依据。方法 :采用预先设计的量表,对344例轻度认知障碍患者进行流行病学调查,通过因子分析提取证素。结果:因子分析提取7个公因子,病位要素为心、肝、脾、肺、肾,相应的病性要素分别为精亏、气虚、血虚、阴虚、阳虚、痰、血瘀、气滞,与临床实践相符合。结论:采用因子分析法对轻度认知障碍进行证素研究是可行的,可为本病的辨证论治提供依据。

Objective：To investigate the syndrome elements of mild cognitive impairment to provide objec- tive evidence for syndrome differentiation and treatment. Methods： 334 patients of mild cognitive impairment were investigated by a predesigned scale. Syndrome elements were summarized with factor analysis. Results：There were 7 common factors picked up by factor analysis. Syndrome elements of disease location were heart, liver, spleen, lung, kidney, and respectively syndrome elements of disease characteristic were essence deficiency, qi deficiency, blood deficiency, yin deficiency, yang deficiency, phlegm, blood stasis, qi stagnation, which was consistent with clinical observation. Conclusion：h is feasible that factor analysis was applied to syndrome ele- ments of mild cognitive impairment, and it was considered that the result can provide objective evidence for syn- dreme differentiation and treatment.