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种植窗期子宫动脉血流及子宫内膜微血管密度与胚胎种植结局的相关性探讨 被引量:3

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摘要 目的:探讨种植窗期子宫动脉血流及子宫内膜微血管密度对胚胎种植结局的影响。方法:体外受精-胚胎移植(IVF-ET)治疗的30例患者,随访IVF-ET结局,根据是否临床妊娠及至少有2次或2次以上的IVF助孕失败史,分为妊娠组和反复种植失败组。三维超声检测种植窗期子宫动脉搏动指数,免疫组化SP法检测子宫内膜血管内皮细胞标记物F8因子。结果:①F8因子特异性的表达于血管内皮细胞,妊娠组微血管密度(5.10±1.28),高于反复种植失败组(3.13±1.1),差异有统计学意义(t=-3.87,P<0.05)。②反复种植失败组和妊娠组子宫动脉搏动指数分别为(0.85±1.51,0.93±0.24),差异无统计学意义(t=-0.98,P>0.05)。结论:种植窗期子宫内膜微血管密度临床妊娠组高于反复种植失败组,对预测胚胎移植结局有一定的临床意义;子宫动脉搏动指数对胚胎移植结局的影响,两组之间无统计学差异,有待进一步探讨。
出处 《陕西医学杂志》 CAS 2014年第2期160-161,共2页 Shaanxi Medical Journal
基金 陕西省科技攻关项目(2010K15-06-05)
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参考文献1

  • 1LI GuoHua1, HUANG Wei1, XIA QingJie2, YANG KaiXuan3, LIU RaoFang1, ZHU HuiLi1 & JIANG Wei4 1 Department of Reproductive Endocrinology, West China Second University Hospital, Sichuan University, Chengdu 610041, China,2 West China Research Laboratory of Molecular Genetics, Sichuan University, Chengdu 610041, China,3 Department of Pathology, West China Second University Hospital, Sichuan University, Chengdu 610041, China,4 Department of Pathology, West China Hospital, Sichuan University, Chengdu 610041, China.Role of uterine natural killer cells in angiogenesis of human decidua of the first-trimester pregnancy[J].Science China(Life Sciences),2008,51(2):111-119. 被引量:7

二级参考文献24

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