植物氧化还原蛋白质组学的研究进展

Advances in Plant Redox Proteomics

植物氧化还原调节参与细胞的每一个代谢,影响细胞稳态和能量平衡。植物中氧化还原翻译后修饰在调节酶活性和控制生理过程中具有重要的意义。在众多研究蛋白氧化应激翻译后修饰的技术中,尤以蛋白质组分析方法最适合。对蛋白质可逆的氧化还原翻译后修饰、氧化应激、氮化应激、抗病防御和细胞氧化还原应激与调控进行了综述,并探讨了氧化还原蛋白质组学的研究前景。

Plants redox control can be exerted over virtually every cellular metabolic pathway affecting metabolic homeostasis and energy balance. Accumulating evidence also underscored the importance of redox post-translational modifications in regulating enzymatic activities and controlling biological processes in plants. Among the techniques developed for the identi cation of oxidative stress-induced modi cations on proteins, proteomics appears to be the best-suited approach. The present review article focused on reversible redox protein modi cations and on three main processes, namely oxidative and nitrosative stress, defense against pathogens, cellular redox response and regulation, the research prospects of redox proteomics were also explored.