异丙酚和瑞芬太尼靶控静脉麻醉的诱导和术后苏醒过程评价

Propofol and remifentanil target-controlled intravenous anesthesia induction and postoperative recovery process evaluation

目的探讨异丙酚和瑞芬太尼靶控静脉麻醉的诱导和术后苏醒过程。方法将80例ASAⅠ～Ⅱ级择期行腹腔镜胆囊切除术患者随机分为对照组与观察组各40例。对照组行静吸复合麻醉,观察组行异丙酚瑞芬太尼靶控静脉麻醉。结果两组患者麻醉诱导时,DBP差异有统计学意义(P<0.05),SBP、MAP及HR相比,差异无统计学意义(P>0.05);两组诱导时各时点OAAS评分差异均有统计学意义(P<0.05);两组患者VRS评分相比,差异均有统计学意义(P<0.05);观察组定向能力恢复时间、离开术后恢复室时间均显著低于对照组(P<0.05)。结论异丙酚瑞芬太尼靶控静脉麻醉用于胆囊切除术效果显著,且苏醒过程较好,值得在临床推广并应用。

Objective To investigate the effects of propofol and remifentanil target-controlled intravenous anesthesia induction and postoperative recovery process. Methods A total of 80 patients ASA Ⅰ～Ⅱ grade elective laparoscopic i cholecystectomy were divided into control group and observation group randomly according to balloting, 40 cases each. Control group underwent inhalation anesthesia, propofol remifentanil group underwent observation target-controlled intravenous anesthesia. Results Two groups of patients during induction of anesthesia, DBP difference was statistically significant （P 〈 0.05）, the difference of SBP, MAP and HR was not statistically significant （P 〉 0.05）; groups induction of the indicators were statistically significant differences （P 〈 0.05）; The observation group OAAS score at different time J had statistically significant differenc compared with the control group （P 〈 0.05）; Two groups of patients perioperative VRS score of comparison, the differences were statistically significant （P 〈 0.05）; The observation group targeting capa- bilities recovery time , leave the recovery room time were significantly lower than the control group（P 〈 0.05）. Conclusion Remifentanil target-controlled propofol intravenous anesthesia for cholecystectomy among patients, the effect is significant, and the awakening process is better, it is worth to be promoted and applied in clinic.