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复合Vit B联合转移因子治疗消化道肿瘤化疗后口腔溃疡疗效观察 被引量:3

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摘要 胃肠道肿瘤患者术后辅助全身化疗有助于降低术后肿瘤复发、转移,目前临床上多采用奥沙利铂联合氟尿嘧啶静脉泵人化疗方案,化疗药在杀死肿瘤细胞同时,也会对增值旺盛的的组织及细胞产生毒性反应,加之化疗期间患者免疫力低下,导致口腔黏膜发生溃疡。据统计,一般常规接受化疗的患者,其口腔黏膜炎的发生率约66%~75%,而泵注5-氟尿嘧啶(5-FU)持续化疗的口腔黏膜炎的发生率更高,导致患者对治疗产生恐惧,甚至中断治疗。因此,及时有效地治疗口腔溃疡具有重要意义。目前治疗口腔溃疡的药物较多,普外科采用口服复合VitB联合转移因子局部注射治疗化疗后口腔溃疡,具有见效快,使用方便,效果好等优点。
机构地区 解放军
出处 《华南国防医学杂志》 CAS 2013年第12期926-927,共2页 Military Medical Journal of South China
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