摘要
作为一种新的基因治疗方法,小干扰RNA(small interfering RNA,siRNA)载体技术的发展,对许多疾病的临床治疗起着至关重要的作用。本文根据近年来国内外文献报道,将siRNA非病毒纳米载体研究进展进行了综述,并分析了现阶段存在的问题,展望了今后的发展方向。
As a new genic therapy method, development of small interfering RNA (siRNA) delivery vehicles is very important for clinical treatment of many diseases. According to the domestic and abroad literatures in recent years, studies of non-viral nanoparticle of siRNA were reviewed. At the same time, the issues existing in present stage and future development were discussed.
出处
《药品评价》
CAS
2013年第24期6-9,19,共5页
Drug Evaluation
关键词
纳米粒
非病毒递送载体
研究进展
siRNA
siRNA
Nanoparticles
Non-viral Delivery Carriers
Research Progress