慢性紧张型头痛与睡眠障碍的相关性研究

Study on correlation between chronic tension type headache and sleep disturbance

目的 探讨慢性紧张型头痛（chronic tension type headache,CTTH）与睡眠障碍的关系,评价睡眠障碍对慢性紧张型头痛的发生、发展及头痛病理生理的影响.方法 依据国际头痛学会2004 ISH-Ⅱ头痛性疾病的分类和诊断标准,选取2012年4月至2013年8月我院神经内科门诊及住院符合慢性紧张型头痛诊断的患者141例,根据头痛程度分为轻度头痛、中度头痛、重度头痛三组,对纳入研究患者性别、年龄、失眠情况、疼痛程度、医后随访、健康指导等指标进行研究,分析睡眠障碍与慢性紧张型头痛发病原因、头痛严重程度等因素的关系.结果 慢性紧张型头痛患者睡眠障碍的发生率为49.6％,与于守臣等调查的正常人群睡眠障碍发生率9.4％有明显的统计学差异（x2=153.63,P＜0.001）,中、重度头痛患者睡眠障碍的发生率明显高于轻度头痛患者（x2=11.017,P＜0.05）,慢性紧张型头痛患者睡眠障碍与性别及家族史无明显相关性（P＞0.05）.结论 慢性紧张型头痛与睡眠障碍存在明显相关性,睡眠障碍可能是慢性紧张型头痛最重要的病因,临床医生应重视慢性紧张型头痛患者睡眠质量,治疗睡眠障碍可能对慢性紧张型头痛的预防及治疗有积极作用.

Objective To study the correlation between chronic tension type headache （CTTH） and sleep disturbance,evaluate the influence of sleep disturbance and CTT＇H occurring,developing and pathophysiology.Methods According to the diagnostic criteria of International Headache Society 2004 ISH-Ⅱ,we selected 141 CTTH patients from our neurology department in our hospital from April 2012 to August 2013.According to the level of headache,the patients were divided into three groups including mild,moderate and serious groups.Age,gender,sleep disturbance,headache levels were researched and analyzed respectively to understand the correlation among the aetiological agent of sleep disorders and CTTH level.Results The insomnia incidence rate of CTTH was 49.6％,statistically significant different from the incidence rate of normal people as 9.4％ from Yu Shouchen＇ research （x 2=153.63,P ＜ 0.001）.The insomnia incidence rate of moderate and serious patients was higher than that of mild patients （x2=11.017,P ＜ 0.05）.There was no correlation between insomnia and gender,family history of CTTH patients.Conclusion There is obvious correlation between CTTH and sleep disturbance.Sleep disturbance is probably the important cause of CTTH.Clinic doctors should pay attention to the sleep problems of CTTH patients.Treating sleep disturbance could probably have positive prevention and treatment effect to CTTH patients.