正确理解与合理实施浅镇静策略

The correct understanding and right implementing of light sedation strategy

浅镇静是在现有条件下镇静策略优化选择的结果.临床研究表明,不合理深镇静（过度镇静）发生频繁,并且在一定程度上影响机械通气患者的预后.恰当浅镇静不仅能有效避免过度镇静的危害,而且通过减少焦虑及其他伤害刺激的传入能有效降低生理与心理应激,保证机械通气和其他高级生命支持治疗的有效性,提高患者的舒适性和安全性.然而,在现有条件限制下,浅镇静实施的可靠性不足,容易发生过浅镇静,与过度镇静一样对机体产生不良影响,同样可能导致不良预后.因此,浅镇静的临床合理实施有待进一步深入研究.

Light sedation is the consequence of sedation strategy optimization based on current clinical practice. Shown by previous studies, suboptimal sedation （mostly deep sedation） occurred frequently, and partly impacted the outcomes of mechanically ventilated patients. Except for getting the patients rid of risk in deep sedation, appropriate light sedation reduces the physical and metal stresses through anxiety relief and block of harmful stimuli, maintains the efficacy of mechanical ventilation and other advanced life support skills, and finally improves patients＂ comfort and safety. Limited by current clinical status for sedation practice, however, light sedation is inadequate reliable, and apt to be extremely light, which will harm the host like the deep sedation, and consequently worsen the outcomes too. Thus, further research on the right implementation of clinical light sedation is needed.