羚黄散治疗急性非特异性下尿路感染下焦湿热证的临床研究

Effect of Linghuang Powder for Acute Nonspecific Lower Urinary Tract Infection with Lower-Jiao Damp-Heat Syndrome

目的 :评价羚黄散治疗急性非特异性下尿路感染下焦湿热证的疗效和安全性。方法 :采用随机对照方法 ,将 4 1 4例患者分为治疗组、对照组和开放治疗组 ,以观察羚黄散对急性非特异性下尿路感染的临床疗效及安全性。结果 :羚黄散治疗组临床近期疗效的愈显率为 71 .78% ,总有效率为 92 .0 2 % ;尿常规治疗后总改善率为 95.2 1 % ,尿细菌学治疗后总改善率为 79.37%。羚黄散治疗组优于对照组 (P <0 .0 1 )。

Objective: To assess the effect of Linghuang powder (LHP) in treating acute nonspecific lower urinary tract infection (ANLUTI) with lower-Jiao damp-heat syndrome and evaluate its safety. Methods: A randomized controlled design was adopted. Four hundred and fourteen patients were allocated to LHP treatment group, control group and open treatment group. Results: The markedly effective rate of short-term treatment with LHP was 71.78%, and the total effective rate was 92.02%, the total rates of improving urine routine and urine bacterium were 95.21% and 79.37% respectively in LHP treatment group. Conclusion:The effect of LHP for ANLUTI with lower-jiao damp-heat syndrome is better than that in the control group (P< 0.01).