青年人胃癌46例临床病理分析

The clinicopathological features of gastric cancer in46 young patients

目的 :探讨青年人胃癌的临床、病理特点 ,分析误诊的原因。方法 :对1980年1月～1995年1月间经手术治疗、病理检验诊断的527例胃癌患者进行回顾性分析 ,着重对≤35岁青年人胃癌进行分析 ,并与其他年龄组胃癌进行比较。结果 :本组青年人胃癌患者中女性少于男性 ,男女之比为1∶0.77;5年生存率低于其他年龄组胃癌患者(P<0.05) ;本组最多见的大体形态为BorrmannⅢ型和Ⅳ型 ,占87 % ;其病理学类型主要是低分化腺癌(37 %)、粘液细胞癌(26.1%)和未分化癌(19.6%)。结论 :青年人胃癌发病率低、病程短、恶性程度高、预后差 ,一旦确诊 。

Objective:To investigate the clinical and pathological features of gastric cancer of young persons,and to analyze the reasons of misdiagnosis.Methods:A number of 46 young patients aged younger than 35 years with gastric cancer suffering surgical treatment were retrospectively reviewed with clinical and pathological characters,and was compared with other age groups.Results:The cases of young women (in total women patients with gastric cancer) was lesser than young man in this group,the man woman ratio was 1∶0.77.The five year survival rate was lower than other age groups.Borrman Ⅲ and Ⅳ were founded mostly in pathomorphologic classifications,and the rate was 87%. The pathological classifications were poorly differentiated adrenocarcinema (37%), mucocellular carcinoma(26.1%) and undifferentiated carcinoma (19.6%)mainly.Conclusions:The course of gastric cancer for young persons was short with a high degree of maligant and a poor prognosis,although the incidence was low for them.So as soon as it was confirmed by diagnosis,an operation should be performed soonly.