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异丙酚复合氯胺酮静脉麻醉应用于小儿扁桃体切除术 被引量:2

Propofol-Ketamine Compound Used for Transvenous Anaesthesia in Children's Tonsillectomy
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摘要 目的:观察异丙酚复合氯胺酮静脉麻醉用于小儿扁桃体切除术的效果,并与氯胺酮与羟丁酸钠复合进行对比。方法:择期手术患者48例,随机分为实验组(n=24),对照组(n=24)。异丙酚诱导剂量为2mg/kg,维持4mg·kg^(-1)·h^(-1),氯胺酮诱导剂量2mg/kg,连续监测MAP,HR及sPO_2,记录起效时间和清醒时间。结果:实验组起效时间和清醒时间明显短于对照组(P<0.01),两组均有sPO_2下降,无统计学差异(P>0.05)。结论:在小儿扁桃体切除术中应用异丙酚复合氯胺酮静脉麻醉是较好的麻醉选择。 Objective:To observe the effect of propofol-ketamine used for transvenous anaesthesia in children's tonsillectomy and compare it with ketamine-r-hydroxybutyrate sodium in anaesthesia effect. Methods : 48 cases were divided into experimental group (propofol-ketamine)(n =24) and control group (ketamine-y-hydroxybutyrate sodium)(n =24) randomly. The propofol dose for anaesthesia induction was 2 mg/kg and the dose for maintenance was 4mg·kg-1·h-1 ,and the ketamine dose was 2mg/kg. MAP, HR and sPO2 were continuably and the times of ouset and recovery were recorded. Results: The times of ouset and recovery in experimental group were shorter than that in control group (P<0.01). sPO2 was reduced in both groups, and there was no difference in statistics (P > 0.05). Conclusion: The propofol-ketamine compound is better than ketamine-γ-hydroxybutyratesodium compound for transvenous anaesthesia in children's tonsillectomy.
出处 《医学理论与实践》 2001年第2期114-115,共2页 The Journal of Medical Theory and Practice
关键词 异丙酚 氯氨酮 麻醉 扁桃体切除术 儿童 Propofol, Ketamine, Anaesthesia, Tonsillectomy
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  • 1郭朝斌,郭毅,孙洁.三例幼儿扁桃体手术麻醉意外的分析[J].临床误诊误治,1996,9(6):282-282. 被引量:1
  • 2刘俊杰 赵俊.现代麻醉学[M](第2版)[M].北京:人民卫生出版社,1996.274.
  • 3宁连成 张景云 李新.小儿扁桃体摘除术麻醉中意外与并发症.临床麻醉学杂志,1996,12(6):383-384.
  • 4魏志成 黄强 郭新春 等.儿童扁桃腺摘除术应用全身麻醉的体会.临床麻醉学杂志,1996,12(3):168-169.
  • 5朱风萍 赵建平 张胜利.氯胺酮静脉复合麻醉用于小儿扁桃体切除术的探讨,附90例分析[J].临床麻醉学杂志,1996,12(3):166-167.
  • 6Randall DA, Hoffer ME. Complicatoins of tonsillectomy and adenoidectmy [J]. Otolaryngol Head Neck Surg, 1998,118 ( 1 ) : 61 - 64.
  • 7刘鹏斌 陈宇 张小琴.气管内吸入麻醉在小儿扁桃体摘除术中的应用体会[J].临床麻醉学杂志,1998,14(6):383-383.
  • 8庄心良,曾因明,陈伯銮主编.现代麻醉学.北京:人民卫生出版社,2003.442.
  • 9Randall DA, Hoffer ME. Complicatoins of tonsillectomy and adenoidectomy. Otolaryngol Head Neck Surg,1998,118(1):61-68.
  • 10李和珍,李玲霞,李双成,武永乐.口腔插管静脉复合麻醉用于小儿扁桃体切除术麻醉体会[J].医学理论与实践,1999,12(12):720-721. 被引量:1

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