血清PSA值升高的BPH患者前列腺液中白细胞状态的研究

While cell count in prostate secretion from benign hyperplasia prostate patients with elevated serum PSA

目的了解血清前列腺特异性抗原(PSA)值升高的良性前列腺增生(BPH)患者前列腺液中白细胞的状态,探讨血清PSA值升高与前列腺液中白细胞的关系。方法获取53例病理证实BPH患者的前列腺液,并分别计数、分析前列腺液体积、前列腺液中白细胞密度和白细胞总数与患者年龄、PSA值、前列腺总体积的相关性。结果患者的白细胞密度、白细胞总数与PSA值呈明显正相关(均P<0.01)。结论血清PSA值升高可能与前列腺液中白细胞数升高有关,对于血清PSA值升高的BPH患者可先行抗炎治疗,再行PSA复查,这样可以减少一些不必要的前列腺穿刺。

Objective To examine while cellcount in prostate secretion from benign hyperplasia prostate （BHP） patients with elevated serum PSA. Methods Prostate secretion samples were obtained from 53 BHP patients with elevated PSA before transrectal prostatic biopsy or transurethal resection of prostate.The number of leukocytes in the prostate secretion was counted, and the correlation of white cellcount with age, PSA and prostate volume was analyzed. Results The white cellcount and the density of white cells in prostate secretion were significantly correlated with serum PSA levels. Conclusion Serum PSA levels may be associated with the increased white cellcount in prostate secretion, which indicating that antibiotics should be given to BHP patients with elevated serum PSA to avoid unnecessary prostate biopsy.