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关注糖尿病治疗新方法的转化医学研究进展

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摘要 近30多年来,随着国民经济发展和生活方式转变,国人的疾病谱出现了显著的变化,以糖尿病为代表的各种慢性疾病快速流行,使我国医疗保障体系面临了前所未有的巨大压力。慢性疾病通常是多种病因所致的复杂疾病,解决慢性疾病的问题需要基础学科与临床学科之间开展多学科联合研究。1996年,《柳叶刀》杂志上首次出现“转化医学(translational medicine)”一词,转化医学包括“从实验台到病床旁(bench to bedside)”和“从病床旁到实验台(bedside to bench)”两个方面[1]。
作者 洪天配
出处 《中国医学前沿杂志(电子版)》 2014年第1期1-3,共3页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
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  • 1Geraghty J. Adenomatous polyposis coli and translational medicine[J].{H}LANCET,1996,(9025):422.
  • 2Elrick H,Stimmler L,Hlad CJ Jr. Plasma insulin response to oral and intravenous glucose administration[J].{H}Journal of Clinical Endocrinology and Metabolism,1964,(10):1076-1082.
  • 3Elashoff M,Matveyenko AV,Gier B. Pancreatitis,pancreatic,and thyroid cancer with glucagon-like peptide-1-based therapies[J].{H}GASTROENTEROLOGY,2011,(01):150-156.
  • 4Singh S,Chang H-Y,Richards TM. Glucagon-like peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus:a population-based matched case-control study[J].JAMA Intern Med,2013,(07):534-539.
  • 5Butler AE,Campbell-Thompson M,Gurlo T. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors[J].{H}DIABETES,2013,(07):2595-2604.
  • 6Nyborg NC,Molck AM,Madsen LW. The human GLP-1 analog liraglutide and the pancreas:evidence for the absence of structural pancreatic changes in three species[J].{H}DIABETES,2012,(05):1243-1249.
  • 7Aston-Mourney K,Subramanian SL,Zraika S. One year of sitagliptin treatment protects against islet amyloid-associatedβ-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice[J].{H}American Journal of Physiology Endocrinology and Metabolism,2013,(04):E475-E484.
  • 8Scirica BM,Bhatt DL,Braunwald E. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus[J].{H}New England Journal of Medicine,2013,(14):1317-1326.
  • 9White WB,Cannon CP,Heller SR. Alogliptin after acute coronary syndrome in patients with type 2 diabetes[J].{H}New England Journal of Medicine,2013,(14):1327-1335.
  • 10Ussher JR,Drucker DJ. Cardiovascular biology of the incretin system[J].{H}ENDOCRINE REVIEWS,2012,(02):187-215.

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