儿童炎症性肌病规范化治疗及预后

Standardized treatment and prognosis children with inflammatory myopathy

儿童炎症性肌病包括感染和免疫相关两类,前者以病毒性肌炎为主,后者以幼年皮肌炎常见。治疗方法根据病因、程度而不同,包括抗感染和免疫治疗,免疫治疗首选激素和免疫抑制剂。是否及时诊治、病损程度、是否合并心肺等器官受累是影响预后的因素。

Inflammatory myopathy include, infective myositis and idiopathic inflammatory myopathy. Infective myositis is mostly caused by virus, while juvenile dermatomyositis is the mainly type in idiopathic inflammatory myopathy in children. Aggressive treatment approaches include anti-infective and immunotherapy, which depend on pathogeny and the extent of disease.Glucoeorticoids and immunosuppressive are the first choice of immunotherapy. Delay of diagnosis and treatment, acute onset of severe symptoms and the complications are asso- ciated with poor outcome.