益心舒胶囊治疗病毒性心肌炎的临床观察

Efficacy of Yixinshu Capsule for Viral Myocarditis: A Clinical Observation

目的:观察益心舒胶囊对病毒性心肌炎临床疗效。方法:将115例病毒性心肌炎患者以随机抽样法分为治疗组和对照组,其中治疗组60例,对照组55例,2组患者均常规给予5%葡萄糖注射液250 ml+三磷酸腺苷(ATP)40 mg+辅酶A 200 U+维生素C 5.0 g静脉滴注治疗,1日1次,治疗2周;治疗组患者在常规治疗的基础上,口服益心舒胶囊1次3粒,1日3次,疗程为4周。观察治疗前后2组患者的临床症状、心电图及心肌酶谱等变化。结果:治疗组患者临床症状、心电图、心肌酶谱的改变均明显优于对照组,2组比较差异有统计学意义(P<0.05);2组患者治疗前后血尿常规、肝肾功能等各项指标均无异常变化,未见明显不良反应。结论:益心舒胶囊治疗病毒性心肌炎有良好疗效,且安全性好,体现了中药的独特优势。

OBJECTIVE：To evaluate the clinical efficacy of Yixinshu capsules for viral myocarditis. METHODS： A total of 115 patients with viral myocarditis were randomized to either trial group （n = 60 ） or control group （n = 55 ） treated routinely with 5% glucose injection （ 250 ml）, triphosadenine （ATP） （ 40 rag）, coenzyme A （ 200 U） and vitamin C （5.0 g） by drip infusion q. d for weeks; however, the trial group was treated with add-on Yixinshu capsules （3 capsules/time, tid） for 4 weeks. The clinical symptoms, ECG and myocardial zymogram etc in the two groups were followed before and after treatment. RESULTS： The trial group showed better improvement in clinical symptoms, ECG and level of myocardial enzyme than in the control group, showing statistically significant differences between the two groups （ P 〈 0. 05 ）. No abnormal change was noted in either group regarding blood routine, urine routine, hepatorenal function etc before and after treatment. CONCLUSION： Yixinshu capsules is safe and effective for viral myocarditis with unique advantage of traditional Chinese medicine.