浦东新区妊娠期高血压疾病的相关高危因素分析

Risk Factors for Hypertensive Disorder during Pregnancy in Pudong New Area

目的探讨浦东新区妊娠期高血压疾病的发病状况及相关危险因素。方法通过对2009—2012年4 056例本地区常住产妇资料的回顾性分析,研究本地区妊娠期高血压疾病的患病情况,并通过多因素非条件Logistic回归分析影响本地区妊娠期高血压疾病发病的高危因素。结果妊娠期高血压疾病的发生率5.18%,其中妊娠期高血压的发生率2.49%,子前期-轻度发生率0.64%,子前期-重度发生率1.85%,子发生率0.05%,妊娠合并慢性高血压的发生率0.15%。多因素分析显示年龄大(OR=7.610,95%CI:2.322～24.936)、孕前体质量指数高(OR=120.715,95%CI:61.867～235.540)、孕期体质量增加量大(OR=16.219,95%CI:6.219～42.316)均为妊娠期高血压疾病的高危因素。结论年龄大、孕前体质量指数高、孕期体质量增加量大为妊娠期高血压疾病的高危因素,而与怀孕次数无关。

Objective To investigate the epidemiological status and risk factors in hypertensive disorder during pregnancy in Pudong New Area in Shanghai. Methods The retrospective study analyzed data of 4 056 maternal residents in the region from 2009 to 2012. The prevalence of hypertensive disorders in pregnancy was analyzed. The related factors for the hypertensive disorder during pregnancy were evaluated by multivariate unconditional logistic analysis. Results The in-cidence of hypertensive disorder during pregnancy was 5.18%, including gestational hypertension 2.49%, preeclampsia-mild 0.64%, preeclampsia-severe 1.85%, eclampsia 0.05%and pregnancy with chronic hypertension 0.15%. The multivari-ate unconditional logistic regression analysis showed that the advanced age （OR=7.610, OR95%CI：2.322-24.936）, the high body mass index （BMI） before pregnancy （OR=120.715,OR 95%CI：61.867-235.540） and the excessively increased BMI during pregnancy （OR=16.219,OR 95%CI：6.219-42.316） were risk factors for hypertensive disorder during pregnancy. Conclusion The risk factors for hypertensive disorder during pregnancy are advanced age, the high BMI before pregnancy and the excessively increased BMI during pregnancy. The hypertensive disorder during pregnancy has no relation with the number of pregnancies.