兰州市流感样病例选择对流感病毒检出率的影响因素分析

Epidemiologic features of influenza like illness in Lanzhou city of China

目的研究兰州市流感样病例的选择对流感病毒检出率的影响因素。方法收集兰州市两家省级哨点医院2010—2011年呼吸道症候群监测信息系统中采集了咽／鼻拭子标本的流感病例资料和流感病毒核酸检测结果进行logistic回归分析。结果流感样病例中流感病毒检出率为20．72％（81／391），两家哨点医院检出率差异无统计学意义，性别、体温、门急诊／住院差异无统计学意义（P〉0．05），年龄、发病季节、是否伴有全身中毒症状和采样一送检时间差异有统计学意义（P〈O．05）。结论兰州市流感样病例中15～64岁年龄组的流感病毒检出率高，冬春季是流感的流行季节，伴全身中毒症状病例的流感病毒检出率高于不伴该类症状病例，应加强对这部分人群及时采集标本，且采集病例标本后应及时送检，并加强我国流感样病例评估研究。

Objective To study the epidemiologic characteristics of influenza like illness in Lanzhou city of Chi- na. Methods Respiratory syndrome data from two provincial sentinel hospitals during 2010--2011 in Lanzhou city of China were collected. Analysis was done by using Logistic regression analysis. Results Among a total of 391 influenza like illness patients, the positive rate of influenza virus is 20.72% （81/391） . Gender, body temperature and outpatient emergency care/hospitalization were not the significant factors affecting the positive rate. Epidemic season, patients with systemic toxic symptoms, age and the duration from sample collection to detection are the major factors influencing the positive rate. Conclusions The positive rate of people with ages of 15-64 was higher in Lanzhou city of China. Spring and winter are the epidemic seasons of influenza. The positive rate of influenza virus in cases with systemic toxic symptoms was higher than that without the systemic toxic symptoms.