愈痔膏体外抗菌作用研究

Study on in Vitro Antibacterial Activities of Yuzhi Ointment

目的 :研究观察愈痔膏的体外抗菌作用。方法 :采用平皿二倍稀释法测定了愈痔膏对临床分离的 170株常见的革兰氏阳性及革兰氏阴性菌的体外最小抑菌浓度 (MIC)。结果 :该药对金黄色葡萄球菌、大肠杆菌、普通变形杆菌、痢疾杆菌及枸橼酸杆菌的 MIC5 0 分别为 3.9,3.9,7.8,15 .6和 31.3 mg/m l。结论 :愈痔膏对上述部分菌株有较强的抑制作用。

Objective: To evaluate in vitro antibacterial activities of Yuzhi ointment. Methods: Minimal inhibitory concentrations (MIC) of Yuzhi ointment was determined by double broth dilution method against common clinical G + and G bacteria. Results: For Stapanrens, Escherichia coli, Proteus vulgaris, Dysenterg bacillus and Citrobacter, the MIC 50 of Yuzhi ointment were 3.9,3.9, 7.8, 15.6 and 31.3 mg/ml, respectively. Conclusion: Yuzhi ointment exhibited strong inhibitory activities against the above bacteria.