摘要
为了从超微水平观察手法治疗大鼠膝骨关节炎的效果 ,采用结扎大鼠双侧股静脉造成下肢骨内高压的方法建立模型 ,术后 4周起予以手法治疗 ,每 3天 1次 ,同时设立正常组 ,空白组及透明质酸钠阳性对照组。分别于手术后 8、16、2 0周取材 ,取股骨外髁进行扫描电镜观察。结果发现除正常组外 ,其余各组病变均进行性加重 ,但手法组和透明质酸钠组病理改变较空白组轻。
To observe the effect of knee joint osteoarthritis by manipulation through scanning electron microscope.Twenty four Wistar rats were ligated in both femoral veins,the randomized three groups,the group without treatment,the manipulation group and the sodium hyaluronate injection group.Other three rats without operation consist the normal group.The manipulation group and the sodium hyaluronate injection group were treated 4 weeks after operation.The animals were sacrificed at 8,16 and 20 weeks postoperatively.The external femoral condyle was excised and prepared for the scanning electron microscopic study.The result reveals the degenerative changes of articular cartilage in the manipulation group and the sodium hyaluronate group are lesser than that in the group without treatment.This confirms manipulation is effective to prevent and treat knee joint osteoarthritis.
出处
《中医正骨》
2001年第1期3-4,共2页
The Journal of Traditional Chinese Orthopedics and Traumatology
基金
国家自然基金资助项目
