基于纳米金膜的双酚A分子印迹传感器研究

Study on bisphenol A imprinted sensor based on the film of gold nanoparticles

通过电化学和分子印迹技术,在金基底表面成功制备出基于三维纳米金膜修饰的双酚A(BPA)分子印迹传感器电极。扫描电镜、透射电镜表征和电化学分析结果表明,电化学沉积法可以使纳米金规则成粒,并均匀成膜;纳米金膜使电极表面具备三维结构;纳米金颗粒(AuNPs)可以在分子印迹聚合物(MIPs)中形成内镶嵌结构,使电极表面电导率显著增高。在对BPA的检测中,MIPs-AuNPs-Au电极的响应信号强度约是MIPs-Au电极的2.6倍,检测限为1.47×10-8mol/L。而且,MIPs-AuNPs-Au电极具有良好的选择性与稳定性。

The gold nanoparticles （AuNPs）modified molecularly imprinted polymers （MIPs）sensing electrode towards bisphenol A has been made by electrochemical methods and molecular imprinting technique on the sur-face of the gold electrode substrate.SEM,TEM and electrochemical analysis were employed to characterize the films on electrode.The results show that the electrochemical deposition method can make the gold nanoparticles grow regularly and the obtained film uniform.AuNPs modified Au electrode has a three-dimensional structure on the surface,and part of gold nanoparticles can be found within the mosaic structure in the MIPs,which in-creases the surface conductivity of the electrode significantly.The signals response to bisphenol A show that the MIP-AuNPs-Au electrode has a 2.63 times higher response compared to the MIPs-Au electrode and its detection limit was 1.47＆#215;10 -8 mol/L in detecting bisphenol A.Besides,the MIPs-AuNPs-Au electrode has a good selec-tivity towards bisphenol A and favorable stability.