急性脑梗死后抑郁治疗的临床研究

Clinical study of the treatment of depression after acute cerebral infarction

目的观察急性脑梗死后抑郁的不同治疗方法对神经功能康复的影响。方法将入选的88例患者分为对照组、心理治疗组、路优泰治疗组及心理并路优泰治疗组,每组22例,应用汉密尔顿抑郁量表(HAMD)及美国国立卫生研究卒中量表(NIHSS)对患者治疗前和治疗后进行评分分析。结果治疗前各组HAMD评分及NIHSS评分差异无统计学意义(P>0.05);各组NIHSS和HAMD评分治疗前后比较,差异有统计学意义(P<0.05);治疗后其他3组与对照组相比,HAMD评分及NIHSS评分差异有统计学意义(P<0.05);治疗后心理并路优泰组与心理治疗组及路优泰组相比,HAMD评分及NIHSS评分差异有统计学意义(P<0.05)。结论心理治疗、路优泰治疗均对脑梗死后抑郁神经功能康复有明显的疗效,心理治疗联合路优泰治疗效果最佳。

Objective To study the effects of different treatments to depression after acute cerebral infarction. Methods The selected patients were divided into control group, psychotherapy group, neurostan treatment group and psychotherapy combined neurostan treatment group. Applications Hamilton Depression Rating Scale（HAMD）and the U.S. National Institutes of Health Stroke Scale Studies（NIHSS） on patients before and after treatment were scored analysis. Results HAMD and NIHSS scores difference in each group was not statistically significant before treatment（P〉0.05） ;NIHSS and HAMD scores difference was significant for every group after treatment（P〈0.05） ;The other three groups after treatment compared with the control group, HAMD scores and NIHSS scores difference were significant（P 〈0.05）, After treatment, compared with psychotherapy group and neurostan group, the scores of HAMD and NIHSS in psychotherapy combined neurostan group difference were significant（P 〈 0.05）. Conclusion Psychotherapy, neurostan had a significant effect for depression after cerebral infarction, psychotherapy combined neurostan treatment was better.