19例男性乳腺癌临床病理分析

Clinicopathologic Analysis of 19 Male Patients with Breast Cancer

目的分析男性乳腺癌(MBC)的临床病理特征和影响预后的因素。方法对19例MBC患者临床病理资料进行回顾性分析。结果 MBC发病率低,发病年龄大,病程长,病理类型多为浸润性导管癌,易见淋巴结转移。19例MBC患者中PR阳性率为63.16%(12/19),ER阳性率为73.68%(14/19),Her-2阳性率为21.05%(4/19),Ki-67阳性率≥25%者为63.16%(12/19)。结论 MBC较少见,多见于老年人,多为浸润性导管癌,且易经淋巴系统转移,且具有一定的性激素表达水平,应采取内分泌治疗。

Objective To analyze the clinicopathologic characteristics and prognostic factors in male breast canc- er （MBC）. Methods The clinicopathologic data of 19 patients with MBC were analyzed retrospectively. Results MBC had following clinical characteristics： lower morbidity, elderly,longer course, the main pathologic type was in- vasive ductal carcinoma, it could easily transfer by lymphatic metastasis. Among the 19 patients, the positive rate of PR,ER,Her-2 and the positive exponent of Ki-67 ≥25% were 63. 16% （12/19）,73.68% （14/19）,21.05% （4/19）and 63.16% （12/19）. Conclusion MBC is rare,more common in the elderly,more invasive ductal carci- noma,more lymphatic metastasis, and most of patients have a certain sex hormone levels, the patients should re- ceived the endocrine therapy.