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右美托咪啶在全身麻醉中的临床效果观察 被引量:6

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摘要 目的:观察右美托咪啶(DEX)在全身麻醉中的临床效果.方法:选择ASA分级Ⅰ~Ⅱ级全麻下择期手术患者160例,随机分为DEX观察组和生理盐水对照组,每组80例.术前对照组微量泵静注生理盐水10ml,观察组静注DEX0.5 ug/kg.记录两组患者苏醒期心血管反应、躁动程度、术后切口疼痛程度评分.结果:观察组1~2级心血管反应、躁动及术后切口疼痛的发生率均低于对照组(P<0.05).结论:DEX可减少全麻患者苏醒期不良反应的发生.
作者 刘会林
机构地区 唐山市开平医院
出处 《贵阳中医学院学报》 2014年第1期54-56,共3页 Journal of Guiyang University of Chinese Medicine
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  • 1李民,张利萍,吴新民.右美托咪啶在临床麻醉中应用的研究进展[J].中国临床药理学杂志,2007,23(6):466-470. 被引量:483
  • 2张海山.全麻复合胸段硬膜外阻滞对气管内插管应激反应的影响[J].第三军医大学学报,2004,26(14):1320-1321. 被引量:5
  • 3Stemp LI,Karras GE Jr.Dexmedetomidine facilitates withdrawal of ventilatory support.Anesthesiology,2006,104(4):890.
  • 4Angst MS,Ramaswamy B,Davies MF,et al.Comparative analgesic and mental dffects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans.Anesthesiology,2004,101(3):744-752.
  • 5Lin TF,Yeh YC,Lin FS,et al.Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia.Br J Anaesth,2009,102(1):117-122.
  • 6Martin E,Ramsay G,Mantz J,et al.The role of the α2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit.J Intensive Care Med,2003,18(1):29-41.
  • 7Hunter JC,Fontana DJ,Hedley LR,et al.Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive,sedative and hypothermic action of dexmedetomidine in transgenic mice.Br J Pharmacol,1997,122(7):1339-1344.
  • 8Khan ZP,Munday IT,Jones RM,et al.Effects of dexmedetomidine on isoflurane requirements in healthy volunteers.1:pharmacodynamicand pharmacokinetic interactions.Br J Anaesth,1999,83(3):372-380.
  • 9Scheinin B,Lindgren L,Randell T,et al.Dexmedetinudine attenuates sympathoadrenal responses to tracheal intubation and reduces the need for thiopentone and peroperative fentanyl.Br J Anaesth,1992,68(2):126-131.
  • 10Raekallio M R, Kuusela E K, Lehtinen M E, et al. Effects of exercise- induced stress and dexamethasone on plasma hormone and glucose con- centrations and sedation in dogs treated with dexmedetomidine [ J ]. Am J Vet Res, 2005, 66 (2) : 260 - 265.

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