长期运动训练对轻中度高血压患者颈动脉内膜中层厚度的影响(英文)

Influence of long-term exercise training on carotid intima-media thickness in patients with mild-moderate hypertension

目的:观察长期运动训练对轻中度高血压患者颈动脉内膜中层厚度(IMT)的影响。方法:92例原发性轻中度高血压患者按数字表法被随机分为常规治疗组(46例)和运动组(46例,在常规治疗基础上进行运动训练),随访1年,测量两组患者治疗前后两组血压、颈总动脉内径、颈动脉IMT,并进行比较分析。结果:与基线值比较,运动组训练1年后收缩压[(176.66±l1.78)mmHg比(130.89±13.01)mmHg]与舒张压[(101.43±6.41)mmHg比(81.71±8.45)mmHg]均明显降低(P均<0.05),颈动脉内径[(6.62±0.97)mm比(6.22±1.01)mm]、颈动脉IMT[(0.98±0.12)mm比(0.84±0.11)mm]显著减小(P均<0.05),且较治常规治疗组治疗后显著减小(P均<0.05)。结论:长期运动训练能有效控制血压,减少颈动脉内径和颈动脉内膜中层厚度。

Objective：To observe influence of long-term exercise training on carotid intima-media thickness （IMT） in patients with mild-moderate hypertension.Methods：A total of 92 patients with essential mild-moderate hypertension were randomly divided into routine treatment group （n=46） and exercise group （n =46,received exercise training based on routine treatment） according to number table.All patients were followed up for one year,and the blood pressure,carotid artery diameter and carotid IMT were measured,compared and analyzed in two groups before and after treatment.Results：There was no significant difference in systolic and diastolic blood pressure before treatment between two groups （P〉0.05）.Compared with baseline value,there were significant decrease in systolic blood pressure [（176.66±11.78）mmHg vs.（130.89±13.01）mmHg],diastolic blood pressure[（101.43±6.41）mm-Hg vs.（81.71±8.45）mmHg],carotid artery diameter[（6.62±0.97）mm vs.（6.22±1.01）mm] and carotid IMT [（0.98±0.12）mm vs.（0.84±0.11）mm] in exercise group after one-year training （P〈0.05 all）,and they were all significantly lower than those of routine treatment group （P〈0.05 all）.Conclusion：Long-term exercise training can effectively control blood pressure,decrease carotid artery diameter and carotid intima-media thickness.