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抑炎因子白介素-37与动脉粥样硬化的关系

Relation ship between anti-inflammatory factor interleukin-37 and atherosclerosis
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摘要 白介素-37是新近发现的白介素-1家族的一新成员。相关研究发现,白介素-37表达于人类的冠状动脉和颈动脉粥样硬化斑块的泡沫细胞,可抑制促炎因子的生成,在炎症性疾病和自身免疫性疾病动物模型中发挥保护性作用。本文就IL-37的基本生物学效应及与动脉粥样硬化的关系作以下综述。 Interleukin （IL） - 37 is a newly discovered new member of IL - 1 family. Relative researches find that IL-37 is expressed on foam cells of human coronary artery and carotid atherosclerotic plaques, which can inhibit production of proinflammatory cytokines and play protective effect in animal models of inflammatory diseases and autoimmune diseases. This article made following overview on fundamental biological effects of IL- 37 and it rela- tionship with atherosclerosis.
作者 贺五一 方红城 苏又苏
机构地区 广东医学院附属南山医院心血管内科
出处 《心血管康复医学杂志》 CAS 2014年第1期110-112,F0003,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 白细胞介素类 动脉硬化 炎症 lnterleukins Arteriosclerosis Inflammation
分类号 R543.509 [医药卫生—心血管疾病]
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参考文献21

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心血管康复医学杂志
2014年 第1期

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