介入栓塞和手术切除在肝癌术后复发治疗中的价值比较

Effect of embolization and surgical resection on patients with recurrent liver cancer

目的:分析介入栓塞和手术切除在肝癌术后复发患者治疗中的应用价值。方法:选择于2012年11月至2013年11月间在本院接受治疗的肝癌术后复发患者作为研究对象,随机分为接受再次手术切除治疗的观察组患者及介入栓塞治疗的对照组患者,比较两组患者治疗后生存率、白细胞(WBC)及甲胎蛋白(AFP)值及肝纤维化指标的差异。结果:(1)观察组患者接受再次手术治疗后,其术后1、3、5年的生存率均显著高于对照组患者(P<0.05);(2)接受治疗前,两组患者的WBC及AFP无明显差异(P>0.05),接受治疗后,观察组患者WBC明显高于对照组,AFP明显低于对照组(P<0.05);(3)接受手术治疗后,观察组患者的各项肝纤维化指标值均明显低于对照组患者(P<0.05)。结论:肝癌术后复发患者接受再次手术治疗可以明显提高其生存率,优化WBC及AFP值,降低肝纤维化程度。

EABSTRACT2 Objective. To observe the effect of embolization and recurrent liver cancer. Methods. Patients with liver cancer recurrence surgical resection on patients with admitted from November 2012 lo November 2013 were selected as study object, and were randomly divided into observation group with sur- gical resection and control group with embolization. Survival rate, WBC and AFP value, liver fibrosis in dex were observed. Results, after treatment, 5-year survival rate after surgery in observation group was significantly higher than control group （P^0.05）. Before treatment, there was no significant difference in WBC and AFP level between two groups （P0.05）, while after treatment, WBC values of observation group were significantly higher than control group patients, AFP values was significantly lower （P%0.05）. After treatment, value of liver fibrosis in observation group was significantly lower than control group （P（0.05）. Oonclusions： Surgery can significantly improve the survival rate of patients with recur- rent liver cancer. It can optimize the value of WBC and AFP, and reduce the degree of liver fibrosis.