摘要
目的 :探索血清乳酸脱氢酶同工酶在恶性肿瘤诊断上的价值。方法 :血清乳酸脱氢酶总活力按崔福生介绍的方法。乳酸脱氢酶采用作者改进的琼脂糖凝胶电泳法。结果 :癌症患者血清乳酸脱氢酶总活力明显增高 ,升高幅度为 3 91%～ 15 3 86 %。同工酶谱则表现为LDH1、LDH2 减低和LDH4 、LDH5增高趋势 ,并表现为LDH3 明显增高 (15 88%～ 5 4 5 1% )和高阳性率(71 43%～ 93 75 % )的特征 ,结论 :血清乳酸脱氢酶总活力及其同工酶的检测 ,对恶性肿瘤的临床诊断有较高的价值。
Purpose: To explore the diagnosis value of serum lactic dehydrogenase and its isoenzymes in carcimoma. Methods: Examination of LDH was done by CUI Fu-sheng's method and LDH isoenzymes by agar-jelly-electrophoretogramic method. Results: Significant elevation of total LDH activity was seen in all kinds of carcinomas. The degrees of elevation was 3.91%～153.86%. Characteristic of the change in activity of LDH isoenzyme pattern was the significant elevation of LDH\-3 and higher positive rate (71.43%～93.75%). LDH\-4 and LDH\-5 was raised, but LDH\-1 and LDH\-2 was declined. Conclusion: The examination of serum LDH and LDH isoenzymes has a great value in the diagnosis of carcinoma.
出处
《癌变．畸变．突变》
CAS
CSCD
2001年第1期29-32,共4页
Carcinogenesis,Teratogenesis & Mutagenesis
关键词
乳酸脱氢酶
癌症
诊断
血清
<Keywords>serum
LDH
cancer
diagnosis
