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丝状真菌降解转化纤维素的机制与遗传改良前景 被引量：5

Progress in bioconversion of cellulose by filamentous fungi and related genetic engineering strategies
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摘要 丝状真菌可以分泌大量纤维素酶及辅助酶来降解纤维素底物,也是目前工业上纤维素酶的主要生产者。回顾并综述了丝状真菌降解转化纤维素的酶系和机制进展,详细总结了组学研究在纤维素酶研究上的新成果,并探讨了提高丝状真菌酶系效率和产量的遗传改良策略。 Filamentous fungi can secrete cellulases and related enzymes to decompose cellulosic substrates,and it is served as the primary producer of cellulase in the industry.This review gives an overview of the enzyme systems for cellulose hydrolysis and the new proposed mechanism of cellulose decomposition in filamentous fungi.The recent progress in cellulase exploration by the ＆quot; omics＆quot;technologies is introduced, and the genetic strategies for improving cellulase efficiency and protein production are discussed.
作者 钟耀华 钱远超 任美斌 汪天虹
机构地区 山东大学生命科学学院 微生物技术国家重点实验室
出处 《生物加工过程》 CAS CSCD 2014年第1期46-54,共9页 Chinese Journal of Bioprocess Engineering
基金 国家重点基础研究发展计划(973计划)(2011CB707403) 国家自然科学基金(31070036 31370135) 山东省优秀中青年科学家科研奖励基金(BS2011SW017) 山东大学自主创新基金(2012TS012)
关键词 纤维素酶 丝状真菌 遗传改良 cellulases filamentous fungi genetic engineering
分类号 Q78 [生物学—分子生物学]
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参考文献55

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二级参考文献77

  • 1汪天虹,钟耀华,王晓利.丝状真菌基因组学研究进展[J].科技导报,2007,25(11):48-52. 被引量：3
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二级引证文献20

生物加工过程
2014年 第1期

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