期刊文献+

丝状真菌降解转化纤维素的机制与遗传改良前景 被引量:5

Progress in bioconversion of cellulose by filamentous fungi and related genetic engineering strategies
下载PDF
导出
摘要 丝状真菌可以分泌大量纤维素酶及辅助酶来降解纤维素底物,也是目前工业上纤维素酶的主要生产者。回顾并综述了丝状真菌降解转化纤维素的酶系和机制进展,详细总结了组学研究在纤维素酶研究上的新成果,并探讨了提高丝状真菌酶系效率和产量的遗传改良策略。 Filamentous fungi can secrete cellulases and related enzymes to decompose cellulosic substrates,and it is served as the primary producer of cellulase in the industry.This review gives an overview of the enzyme systems for cellulose hydrolysis and the new proposed mechanism of cellulose decomposition in filamentous fungi.The recent progress in cellulase exploration by the " omics"technologies is introduced, and the genetic strategies for improving cellulase efficiency and protein production are discussed.
出处 《生物加工过程》 CAS CSCD 2014年第1期46-54,共9页 Chinese Journal of Bioprocess Engineering
基金 国家重点基础研究发展计划(973计划)(2011CB707403) 国家自然科学基金(31070036 31370135) 山东省优秀中青年科学家科研奖励基金(BS2011SW017) 山东大学自主创新基金(2012TS012)
关键词 纤维素酶 丝状真菌 遗传改良 cellulases filamentous fungi genetic engineering
  • 相关文献

参考文献55

  • 1Kubicek C P, Mikus M, Schuster A, et al. Metabolic engineering strategies for the improvement of cellulase production by Hypocrea jecorina[ J ] .Biotechnol Biofuels, 2009,2 : 19. doi : 10. 1186/1754- 6834-2-19.
  • 2Chandel A K, Chandrasekhar G, Silva M B, et al. The realm of cellulases in biorefinery development [ J ]. Crit Rev Biotechnol, 2012,32(3) :187-202.
  • 3Regalbuto J R. Cellulosic biofuels: got gasoline [ J ]. Science, 2009,325 : 822-824.
  • 4Lynd L R, van Zyl W H, McBride J E, et al. Consolidated bioprocessing of cellulosic biomass : an update [ J ]. Curt Opin Biotechno1,2005,16( 5 ) :577-583.
  • 5Greer D. Spinning straw into fuel [ J ]. Biocycle, 2005,46 ( 4 ) : 61-65.
  • 6Wilson D B. Cellulases and biofuels [ J 1. Curr Opin Biotechnol, 2009,20(3) :295-299.
  • 7Percival Zhang Y H, Himmel M E, Mielenz J R. Outlook for cellulase improvement: screening and selection strategies [ J ]. Biotechnol Adv, 2006,24 ( 5 ) : 452-481.
  • 8Himmel M E, Ding S Y, Johnson D K, et al. Biomass recalcitrance: engineering plants and enzymes for biofuels production [ J ]. Science, 2007,315 : 804-807.
  • 9Martinez D, Berka R M, Henrissat B, et al. Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei ( syn. Hypocrea jecorina ) [ J ]. Nat Biotechnol, 2008, 26 ( 5 ) : 553-560.
  • 10Liu G, Zhang L, Wei X, et al. Genomie and seeretomie analyses reveal unique features of the lignocellulolytie enzyme system ofPenicillium decumbens [ J ]. PLoS One, 2013, 8 (2): e55185, doi : 10. 1371/journal. pone. 0055185.

二级参考文献77

  • 1汪天虹,钟耀华,王晓利.丝状真菌基因组学研究进展[J].科技导报,2007,25(11):48-52. 被引量:3
  • 2Selker EU. Epigenetic phenomena in filamentous fungi: useful paradigms or repeat-induced confusion? Trends in Genetics, 1997, 13: 296-301.
  • 3Withers JM, Swift RJ, Wiebe MG, Robson GD, Punt PJ, van den Hondel CA, Trinci AP. Optimization and stability of glucoamylase production by recombinant strains of Aspergillus niger in chemostat culture. Biotechnology and Bioengineering, 1998, 59: 407-418.
  • 4Wiebe MG, Robson GD, Shuster J, Trinci APJ. Evolution of a recombinant (glucoamylase-producing) strain of Fusarium venenatum A3/5 in chemostat culture. Biotechnology and Bioengineering, 2001, 73: 146-156.
  • 5Swift R J, Karandikar A, Griffen AM, Punt PJ, van den Hondel CA, Trinci AP, Wiebe MG. The effect of organic nitrogen sources on recombinant glucoamylase production by Aspergillus niger in chemostat culture. Fungal Genetics and Biology, 2000, 31: 125-133.
  • 6Nevalainen H, Te'o V, Penttila M, Pakula T. Heterologous gene expression in filamentous fungi: A holistic view. Applied Mycology and Biotechnology, 2005, 5:211-237.
  • 7Sims AH, Gent ME, Lanthaler K, Dunn-Coleman NS, Oliver SG, Robson GD. Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo. Applied and Environmental Microbiology, 2005, 71(5): 2737-2747.
  • 8Arvas M, Pakula T, Lanthaler K, Saloheimo M, Valkonen M, Suortti T, Robson G, Penttila M. Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae. BMC Genomics, 2006, 7: 32.
  • 9Medina ML, Kiernan UA, Francisco WA. Proteomic analysis of rutin-induced secreted proteins from Aspergillus flavus. Fungal Genetics and Biology, 2004, 41 327-335.
  • 10Medina ML, Haynes PA, Breci L, Francisco WA. Analysis of secreted proteins from Aspergillus flavus. Proteomics, 2005, 5: 3153-3161.

共引文献12

同被引文献114

引证文献5

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部