肝癌门静脉癌栓非手术治疗的临床效果

Clinical Effect of Non-Operative Treatment of Tumor Thrombus in Portal Vein

目的 探讨在超声引导下经皮穿刺门静脉癌栓直接治疗的临床价值。方法 2 0例肝癌门静脉癌栓患者门静脉直接穿刺或置管。穿刺 16例 ,置管 4例。药物包括 :丝裂霉素C(MMC)、表阿霉素 (EPB)、5-氟脲嘧啶 ( 5-Fu)、甲酰四氢叶酸钙 (CF)、无水酒精及碘油。结果 1例癌栓消失、3例门脉主干部癌栓缩小、6例得到明显控制 ,所有患者临床症状得以改善 ,生存期延长。结论 超声引导下直接门静脉穿刺癌栓治疗是一简单、有效、安全的方法 。

Objective To study clinical value of a new therapy for tumor thrombus of portal vein.Methods Twenty patients received direct puncture to portal vein or tube insertion under ultrasonographic guide.Among them,16 patients received direct injection and 4 had tube insertion.It provided high concentration of anticancer drugs directly to the tumor thrombus.Results The thrombus disappeared only one case,the mass of tumor thrombus decreased in the portal vein trunk in 3 cases and obviously was controlled in 6 cases.The survival time in the group with treatment was longer than in that the control group.Conclusion This method is an effective,safe and easy procedure,it has active significance for advanced hepatic cancer.