摘要
目的研究住院患者医院感染病原菌种类分布及耐药菌变化情况,为指导临床合理用药提供科学依据。方法采用细菌分离鉴定和药敏试验方法,对某医院2012年度住院医院感染患者标本病原学检测结果进行研究与分析。结果该医院在2012年度从住院患者送检的3 027例标本中,共分离到病原菌664株,革兰阴性菌占40.1%,革兰阳性菌占23.5%,真菌占36.5%。革兰阴性杆菌对复方新诺明、先锋Ⅴ、头孢呋辛、氨卞舒巴坦等耐药率均超过50%。革兰阳性球菌对青霉素、苯唑青霉素、阿奇霉素、复方新诺明、庆大霉素等耐药率较高。结论该医院临床分离病原菌对常用抗菌药物的耐药率总体呈上升趋势,提示应加强监测和提高药敏试验率,合理应用抗菌药物。
Objective To study distribution and drug resistant pathogens species change, to provide a scientific basis for rational use of antibiotic. Methods Bacterial isolation, identification and drug sensitive test were used to study and analy- sis the hospital inpatient specimens pathogen detection results in 2012. Results In 2012, 664 strains of pathogens were i- solated from 3 027 hospitalized patients specimen. Gram - negative bacteria accounted for 40. 1% , Gram - positive bacte- ria accounted for 23.5%, fungi accounted for 36. 5% . The resistance rate of Gram -negative bacilli to cotrimoxazole, ce- fazolin, eefuroxime, ampicillin and sulbactam were over 50%. The resistance of Gram - positive cocci to penicillin, oxacil- fin, azithromycin, cotrimoxazole, gentamicin were higher. Conclusion The resistance rate of hospital clinical isolates of pathogens to commonly used antibiotics was rise, which suggested we should strengthen monitoring and increase drug resist- ant testing, rational use of antimicrobial drugs.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第1期35-37,共3页
Chinese Journal of Disinfection
关键词
医院感染
病原菌
种类分布
耐药性
hospital infection
pathogens
species distribution
drug resistant
