冠状动脉病变:影像学与生理学评价

Assessment of Imaging and Physiology in Coronary Artery Disease

近年来,冠心病仍然是世界范围内威胁人类健康的主要死因,冠状动脉造影长久以来一直被认为是评价冠状动脉病变的影像学"金标准"。然而对于一些复杂病变如分叉病变、易损斑块及临界病变等,应用冠状动脉造影评价冠状动脉病变略显局限。因此,为了满足临床需要,新的影像学及生理学评价技术应运而生,目前用于评价冠状动脉病变的有创性或无创性技术有:血管内超声、光学相干断层成像、血流储备分数等。他们各有千秋,并在心血管领域发挥重要的作用。

In the recent years, coronary artery disease remains the leading cause of death that threaten human health worldwide, coro nary angiography has been considered the ＂gold standard＂ for evaluation of coronary artery lesion for a long time. However, coronary angiog raphy has well-known limitations in the detection of complex lesions such as bifurcation lesions, vulnerable plaques and borderline lesions. Thus, new imaging and physiologic techniques are designed to meet the clinical needs. To date,many invasive and non-invasive techniques are employed to assess coronary artery lesions, including intravascular ultrasound, optical coherence tomography, fractional flow reserve, etc. All of them have their own advantages and play essential roles in cardiovascular field.