从脾论强直性脊柱炎

Academic discussion on the Chinese medical treatment strategies based on spleen for ankylosing spondylitis

强直性脊柱炎(AS)是以骶髂关节和脊柱关节慢性炎症为主的自身免疫性疾病。该病目前病因未明,在治疗上比较困难。中医治则多从肾入手,但脾虚作为强直性脊柱炎发生发展过程的病机之一,亦十分重要。从病因而言,肠道黏膜免疫紊乱及肠道菌群紊乱和发病有莫大关联。在治疗过程中,脾湿会导致患者关节肿胀,而且虫类中药、消炎止痛药口服伤胃,会步入服药再伤脾胃的恶性循环。在情绪方面,思虑过度亦可伤脾,使病情缠绵难愈。文章就这几方面探讨脾对AS的意义。

Ankylosing spondylitis is an autoimmune disease which tends to cause chronic inflammation of the sacroiliac joints and the spinal joints as well as degeneration. The disease is currently unknown in cause and is difficult in the treatment. TCM treatment often stresses on nourishing kidney, but as one of the pathogenesis in the development process, spleen deficiency is also very important. Etiologically, the intestinal mucosal immune dysfunction and intestinal flora disturbance of the disease also have great relevance. In the course of treatment, spleen-dampness would lead to joint swelling, and Chinese worm medicine, analgesics will hurt stomach, vicious spiral into drug to hurt the stomach. In the aspect of mood, excessive anxiety can injure spleen, leading illness lingering. This paper discussed these subjects about the effect of the spleen for AS.