黄芪注射液联合磷酸肌酸钠治疗病毒性心肌炎的疗效观察

Clinical Effect Observation of Huangqi Injection Combined with Phosphate Sodium in the Treatment of Viral Myocarditis

目的:探讨黄芪注射液联合磷酸肌酸钠治疗病毒性心肌炎的临床疗效。方法:将92例病毒性心肌炎患者按随机数字表法均分为治疗组和对照组。对照组给予常规基础治疗;观察组在对照组的基础上,加用黄芪注射液和磷酸肌酸钠静脉滴注治疗。治疗2周后,观察对比两组的临床疗效。结果:观察组显效率为67.4%,总有效率为95.7%,对照组分别为43.5%、76.1%,两组显效率及总有效率比较差异均有统计学意义(P<0.05);治疗后两组心肌酶谱CK、CK-MB、LDH均较治疗前明显下降(P<0.05),且治疗后观察组心肌酶谱明显低于对照组,差异有统计学意义(P<0.05)。结论:黄芪注射液联合磷酸肌酸钠治疗病毒性心肌炎疗效确切,可显著改善患者心肌酶谱CK、CKMB、LDH等指标,值得推广应用。

Objective：To explore the clinical effect of huangqi injection combined with phosphate sodium on viral myocarditis. Method：92 patients with viral myocarditis were divided into the treatment group and the control group according to random number table method,the control group received conventional basic therapy,while the treatment group were given huangqi injection and phosphate sodium based on conventional basic therapy, after 2 weeks of treatment,the clinical efficacy of the two group were observed and compared. Result：The efficiency of the observation group and the control group were 67.4%and 43.5%respectively,and the total effective rate were 95.7%and 76.1%respectively,there were statistically significant between the two group on efficiency and total efficiency（P〈0.05）. After treatment,myocardial enzymes CK,CK-MB,LDH were decreased significantly than that of pre-treatment（P〈0.05）,and the myocardial enzymes CK,CK-MB,LDH of the observation group were significantly lower than that of the control group, and the difference was statistically significant（P〈0.05）. Conclusion：Huangqi injection combined phosphate sodium is effective in treatment of viral myocarditis,and the myocardial enzymes such as CK,CK-MB and LDH can be significantly improved,which should be widely applied in clinic.