52例开放性骨折创口感染的病原体分析

Analysis of Pathogens in 52 Cases with Open Fractures Wound Infection

目的:探讨开放性骨折创口感染的细菌类型和预防措施。方法:对52例开放性骨折患者提取创伤边缘组织作为样本进行病原菌鉴定和药敏实验,并对结果作回顾分析。结果:创口感染以金黄色葡萄球菌感染最多(26.92%),其后依次为铜绿假单胞菌、表皮葡萄球菌、绿脓杆菌。绿脓杆菌和铜绿假单胞菌对万古霉素最为敏感,金黄色葡萄球菌对青霉素和氨苄青霉素最为敏感,表皮葡萄球菌对氨苄青霉素最为敏感。结论:对于开放性骨折,反复彻底的清创是预防感染发生的关键,及时做创口病原菌鉴定和药敏试验有助于临床合理准确地应用抗生素,降低创面感染率,提高治疗效果。

Objective：To investigate types of bacteria and prevention measures for open fractures wound infection.Method：The wound edges tissue samples of 52 cases with open fracture were extracted for pathogens identification and susceptibility testing,and the results were retrospectively analyzed. Result：Amounts of Staphylococcus aureus infections in the wound infections were the most（26.92%）,and followed by Pseudomonas aeruginosa,Staphylococcus epidermidis,Pseudomonas aeruginosa.Pseudomonas aeruginosa and Pseudomonas aeruginosa were most sensitive to vancomycin,and Staphylococcus aureus was most sensitive to penicillin and ampicillin,and Staphylococcus epidermidis was most sensitive to ampicillin.Conclusion：The repeated debridement is the key to prevent infection for open fractures, and doing wound pathogens identification timely and susceptibility testing can help applying antibiotics in the clinical reasonably and accurately, reduce wound infection rates, improve clinical effects.