摘要
[目的]观察肠吉泰联合经皮穴位电刺激法治疗腹泻型肠易激综合征(IBS-D)的临床疗效和复发率。[方法]遵循随机、双盲、安慰剂平行对照的设计原则,将242例IBS-D患者分为肠吉泰、肠吉泰联合经皮穴位电刺激、安慰剂3组。按照病情分级特征再次将各组患者分为轻、中、重度进行分层观察研究,以肠道总体症状尺度表评判治疗结果。治疗结束后按1∶1∶1比例将所有治愈和显效的受试者随机分为穴位经皮电刺激组、模拟刺激对照组和空白对照组,电话随访记录受试者复发时间。[结果]肠吉泰和肠吉泰联合经皮穴位电刺激组对肠道总体症状的改善显著优于安慰剂组(P<0.05,<0.01),肠吉泰联合经皮穴位电刺激组较肠吉泰组疗效更显著(P<0.05)。治疗结束后经皮穴位电刺激组的复发率显著低于模拟刺激组和空白对照组(P<0.05)。[结论]经皮穴位电刺激联合肠吉泰比单用肠吉泰治疗有显著的优越性,而且经穴刺激可以有效预防IBS-D的再度复发。
[Objective]To observe the clinical effect and the recurrence rate after treatment of Changjitai combined with percutaneous accupoint stimulation method in the treatment of diarrhea type irritable bowel syndrome. I-Methods]To follow the parallel randomized, double blind, placebo controlled design principle, two hundred and forty-two cases of diarrhea type irritable bowel syndrome patients were divided into Changjitai combined with percutaneous accupoint stimulation and placebo group. According to the patients' condition, each group was sub-divided into mild, medium and heavy layering. Effects were judged according to the bowel symptom scale scores. After the treatment, all cases cured or significantly improved were ran- domly divided into percutaneous accupoint stimulation group, stimulus control group and blank control group, and the telephone follow-up study was made to record the recurrence time. l-Results]Two positive in- terventional groups have got significantly better effects than placebo group. Changjitai combined with per- cutaneous accupoint stimulation group was even better than Changjitai group. After the treatment, recur- rence rate of percutaneous accupoint stimulation group was significantly lower than that of other 2 groups. [Conclusion]Changjitai combined with percutaneous accupoint stimulation group has obvious superiority in improving bowel symptom scale scores,and percutaneous accupoint stimulation can effectively prevent the recurrences of irritable bowel syndrome.
出处
《中国中西医结合消化杂志》
CAS
2014年第1期1-4,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金
上海市科委中药现代化专项课题(No:10DZ1973200)
上海中医药事业发展三年行动计划研究型中医院建设项目(No:ZYSNXD-CC-YJXYY-JS13(S)
关键词
腹泻型肠易激综合征
肠吉泰
经穴
电刺激
diarrhea irritable bowel syndrome
changitai
accupoint
percutaneous stimulation