我院药品不良反应180例分析

Analysis of 180 cases of adverse drug reaction in our Hospital

目的分析我院药品不良反应（ADR）的发生情况及特点，促进我院安全、有效、合理用药。方法对我院2006～2011年上报的180例ADR报告资料进行分类统计和分析。结果180例ADR中，女性ADR的发生率高于男性，男女发生ADR比例为1：2．05；多发于60岁以上的老年人，占23.89％；引发ADR给药方式以静脉给药为主，占82.22％。ADR涉及的药物品种中，居首位的是抗茵药物88例，占48．88％，其中头孢菌素类药物发生例数为30例，占抗菌药物发生例数的34．09％。ADR涉及的器官或系统以皮肤及其附件为主，占57．78％。结论加强合理用药教育，提高医务人员上报ADR的积极性和主动性，确保临床用药安全、有效、经济。

Objective Analysis of hospital adverse drug reactions （ADR） occurrence and characteristics, to promote the hospital safe, effective and rational use of drugs. Methods 2006-2011 reported in our Hospital 180 cases of ADR reporting and classification of statistics and data analysis. Results 180 cases of ADR, the ADR incidence of women than men, male and female ratio of 1：2.05 ADR occurred; multiple people over the age of 60, accounting for 23.89%; Yinfa ADR approach to intravenous administration, accounting for 82.22 %. ADR variety of drugs involved in the first place is that antibacterial drugs 88 cases, accounting for 48.88%, which occurred cephalosporins number of cases to 30 cases, accounting for the number of cases of antibiotic occurred 34.09%. ADR involved organ or system to the skin and its annexes, accounting for 57.78%. Conclusion Rational use of drugs to enhance education, improve the medical staff to report ADR＇s enthusiasm and initiative, to ensure the safety of clinical medicine, effective and economical.