摘要
肿瘤坏死因子相关的凋亡诱导配体 (TNF relatedapoptosisinducingligand ,TRAIL)属于肿瘤坏死因子家族 ,可激活肿瘤细胞的凋亡。本文介绍了TRAIL的结构与功能 。
TRAIL (TNF related apoptosis inducing ligand) belongs to the tumor necrosis factor (TNF) cytokine family ,can induce apoptosis in a wide variety of tumor cell lines. This review introduces research progress on TRAIL from several aspects: the structure and function of TRAIL, the pathway of its inducing apoptosis, TRAIL and cancer treatment, and its foreground.
出处
《生理科学进展》
CAS
CSCD
北大核心
2001年第1期18-22,共5页
Progress in Physiological Sciences
基金
国家自然科学基金重点资助课题!(39830 110 )
