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Pilot study of gated-PET / CT for evaluating myocardial blood-supply and myocardial metabolism in pigs

Pilot study of gated-PET / CT for evaluating myocardial blood-supply and myocardial metabolism in pigs
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摘要 Background As for the patients with coronary arteriosclerosis, the presence of ischemic myocardial survival is significant for the treatment and prognosis. Gated 13N-NH3 and 18SF-FDG PET/CT imaging provides myocardial perfusion, metabolism and cardiac function which can valuate myocardial viability accurately and noninvasively. Methods Four pigs were subjected to bilateral internal mammary artery Y-bypass operation in operating room. The pigs under the anesthetized state were sent to PET center when the operation finished. Then 13N-NH3 gated-PET/CT and 18F-FDG gated-PET/CT were performed. Results The myocardial perfusion and myocardial metabolism is well-distributed of left ventricular wall. The motion of the wall was normal. The ejection function was greater than 50%. Conclusion Gated-PET/CT can be used for noninvasive evaluation of myocardial perfusion, myocardial metabolism and left ventricle function. Background As for the patients with coronary arteriosclerosis, the presence of ischemic myocardial survival is significant for the treatment and prognosis. Gated 13N-NH3 and 18SF-FDG PET/CT imaging provides myocardial perfusion, metabolism and cardiac function which can valuate myocardial viability accurately and noninvasively. Methods Four pigs were subjected to bilateral internal mammary artery Y-bypass operation in operating room. The pigs under the anesthetized state were sent to PET center when the operation finished. Then 13N-NH3 gated-PET/CT and 18F-FDG gated-PET/CT were performed. Results The myocardial perfusion and myocardial metabolism is well-distributed of left ventricular wall. The motion of the wall was normal. The ejection function was greater than 50%. Conclusion Gated-PET/CT can be used for noninvasive evaluation of myocardial perfusion, myocardial metabolism and left ventricle function.
出处 《South China Journal of Cardiology》 CAS 2013年第4期266-271,共6页 岭南心血管病杂志(英文版)
基金 supported by National Science & Technology Pillar Program during the 12th Fiveyear Plan Period(No.SQ2011SF12C03081) Key Program for International S&T Cooperation Projects of China(No.2010DFA32660)
关键词 TOMOGRAPHY emission computed POSITRON gated myocardial imaging tomography emission computed positron gated myocardial imaging
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参考文献11

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