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妊娠期高血压疾病患者血清脂质运载蛋白2水平变化及其意义 被引量：3

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摘要 目的:探讨脂质运载蛋白2(lipocalin-2,LCN2)与妊娠期高血压疾病发病的关系。方法:将在我院产科分娩的妊娠期高血压疾病患者96例(妊娠期高血压疾病组),根据病情轻重分为妊娠期高血压组(38例),轻度子痫前期组(35例)和重度子痫前期组(23例)。采用酶联免疫吸附试验检测所有患者血清LCN2质量浓度,并与40例正常孕妇(正常妊娠组)作比较。结果:正常妊娠组血清LCN2为(22.52±6.05)ng/mL,妊娠期高血压疾病组为(59.19±17.12)ng/mL,两组比较差异有统计学意义(P<0.01);其中,妊娠期高血压组为(42.34±13.12)ng/mL,轻度子痫前期组为(50.35±14.01)ng/mL,重度子痫前期组为(71.41±19.21)ng/mL,轻、重度子痫前期组LCN2水平均明显高于妊娠期高血压组(P<0.05,P<0.01),轻度子痫前期组与重度子痫前期组比较差异有统计学意义(P<0.01)。结论:LCN2水平变化与妊娠期高血压疾病的发病密切相关,并随病情加重而增高。
作者 吴爱民 范玉平
机构地区 江苏省南通市第一人民医院妇产科 江苏省南通市第一人民医院检验科
出处 《南通大学学报（医学版）》 2013年第6期543-544,共2页 Journal of Nantong University(Medical sciences)
关键词 妊娠并发症 高血压病 脂质运载蛋白2
分类号 R714.25 [医药卫生—妇产科学]
  • 相关文献

参考文献10

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二级参考文献14

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共引文献13

同被引文献15

引证文献3

二级引证文献4

南通大学学报（医学版）
2013年 第6期

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