管饲肠内营养对DLD患者疗效的影响

Effect of enteral tube feeding on severe acute diffuse lung disease patients received non-invasive positive pressure ventilation

目的探讨管饲肠内营养对急性重症弥漫性肺疾病(DLD)无创正压通气患者疗效及安全性的影响。方法收治急性重症DLD无创正压通气患者34例,分为管饲组和经口摄食组,比较两组患者住ICU时间、气管插管率、28天死亡率,以及管饲组营养支持前后相关指标的变化。结果与经口摄食组比较,管饲组平均住ICU时间比经口摄食组明显缩短(P<0.05),管饲组治疗后实验室指标均较前改善(P<0.05)。结论管饲肠内营养支持应用安全,是急性重症DLD无创正压通气患者营养支持的首选。

Objective To explore the effect and safety of enteral tube feeding on severe acute diffuse lung disease （DLD） patients received noninvasive positive pressure ventilation （NPPV）. Methods 34 severe acute DLD patients treated with NPPV were divided into the enteral tube feeding group received enteral tube feeding therapy and the oral feeding group received oral feeding therapy. The following items were observed, including duration of ICU stay, rate of trachea cannula,and mortality 28 days after the treatment. The laboratory indexes before and after the treatment were compared in the enteral tube feeding group. Results The duration of ICU stay was obviously shorter in the enteral tube feeding group than in the oral feeding group. The laboratory indexes improved significantly after the treatment in the enteral tube feeding group. Conclusion Enteral tube feeding is a safe method, which should be considered for severe acute DLD patients with NPPV firstly.