非辩证的应用中药注射剂对心脑血管病患者血流变的影响

Effects of TCM injections not based on syndrome differentiation on blood rheology in patients with cardiovascular disease

目的了解非辩证联合应用中药注射剂对血流变的影响。方法随机选择68例具有心脑血管系统疾病且血流变异常的患者,在西医常规用药治疗的基础上根据医生习惯未经辨证的分别加用中药注射剂丹参、血栓通、瓜蒌皮等静滴1个疗程,其中40例只用1种中药注射剂,26例用了2种中药注射剂的联合,分别于用药前后抽血测定患者的血流变指标。结果单联治疗组治疗前后患者的血流变指标无明显改变;联合治疗组治疗后血流变部分指标较前改变,血黏度降低。结论非辩证的应用具有活血化瘀作用的中药注射剂对心脑血管疾病患者血流变的影响较小,联合应用可降低部分血黏度指标,只用一种药物对患者的血流变无明显影响。

Abstract： Objective To investigate the effects of TCM injections treatment not based on syndrome differentiation on blood theology in patients with cardiovascular disease. Methods Total 68 cases of cardiovascular and cerebrovascular system diseases were randomly selected and enrolled in this study. All patients received the conventional Western medi- cine therapy. According to the doctor＇ s habits, traditional Chinese medicine injections （ Salvia, Xueshuantong, Trichosan- thes skin and so on） were administrated for one course not based on syndrome differentiation. 40 patients only received one TCM injection ; other 26 cases received 2 kings of TCM injection. The blood rheology was measured in all patients be- fore and after treatment. Results The blood rheology parameters did not change in the single TCM injection group, but some parameters changed obviously in the combined TCM injection group with a decreased blood viscosity. Conclusion The TCM injections treatment not based on syndrome differentiation shows little effect on the blood rheology parameters in patients with cardiovascular disease. The combination therapy can reduce the level of blood viscosity, but only one medi- cine will have no significant effect.