气相色谱-飞行时间质谱在化合物鉴定方面的应用进展

Progress in Applications of Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry for Identification of Compounds

基于飞行时间质谱的高分辨能力、高采集速率、精确质量全谱采集等特点,该技术已广泛应用与环境监测、食品安全、生物医药等领域中复杂基质的分析。随着仪器的发展,GC-TOF MS将在目标化合物与未知化合物的可靠鉴定方面发挥更大的作用,本文综述了近十年GC-TOF MS在化合物鉴定方面的相关应用并对其发展进行了展望。

Depending on the unique characteristics of high resolution, fast acquisition rates,accurate mass full- spectrum acquisition of Time-of-Flight Mass Spectrometry, it has been widely used in the analysis of complex matrices of environmental test, food safety, biomedical science and other fields. As progressing of the instruments, GC-TOF MS will play a more important role in unequivocal identifications of target or non-target compounds. In this paper, the applications in chemical identification by GC-TOF MS at recent ten years were summarized, and the further development of GC-TOF MS in the future was prospected.