头孢噻肟钠治疗下呼吸道感染的临床效果观察

Clinical effect observation of cefotaxime sodium in the treatment of lower respiratory infections

目的观察头孢噻肟钠治疗下呼吸道感染的临床效果。方法选取本院2011年8月～2013年6月收治的下呼吸道感染患者142例，将其随机分为实验组和对照组各71例，实验组应用头孢噻肟钠进行治疗，对照组应用头孢曲松进行治疗，对比观察两组患者的临床疗效。结果实验组总有效率及显效率明显高于对照组，复发率显著低于对照组，但所需费用高于对照组，差异有统计学意义（P〈0.05）。结论头孢噻肟钠治疗下呼吸道感染，能够有效提高临床疗效，降低复发，但治疗成本高于头孢曲松，在临床应用上应根据患者的具体情况予以选择。

Objective To observe the clinical effect of cefotaxime sodium in the treatment of lower respiratory infections.Methods 142 cases of patients with lower respiratory infections who were admitted to our hospital from August 2011 to June 2013 were selected and randomly assigned into experimental group and control group.The cefotaxime sodium was given to experimental group,while the ceftriaxone was given to control group.The clinical effect of two groups was compared and observed.Results The total effective rate and significant effective rate of the experimental group was significantly higher than that of the control group;recurrence rate was significantly lower than that of the control group;treatment cost was higher than that of the control group.The difference was significant （P〈0.05）.Conclu- sion Cefotaxime sodium in the treatment of lower respiratory infections can improve the clinical effect and lower the re- currence rate,but its treatment cost is higher than ceflriaxone.The treatment is to be determined according to patients＇ conditions in clinical application.