摘要
目的探讨拉莫三嗪单药对部分性发作癫痫患儿脑电活动的影响。方法首次确断为部分性发作癫痫患儿41例加用拉莫三嗪治疗12个月,治疗前后分别行24 h动态脑电图检测,观察脑电图中θ波和痫样放电的情况。结果拉莫三嗪单药治疗41例患儿12个月,脑电图中θ波和痫样放电较治疗前明显减少。结论拉莫三嗪可明显改善部分性发作癫痫患儿脑电图变化,减少部分性发作癫痫患儿癫痫发作,改善癫痫患儿的认知功能。
Objective To investigate the effect of electroencephalogram by lamotrigine monotherapy for focal epilepsy in children.Methods 41 cases of focal epilepsy children were treated by lamotrigine in 12 months,0 electroencephalo- gram wave and epileptiform discharges was observed with 24-hour ambulatory electroencephalogram before and after treatment.Results Electroencephalogram 0 wave and epileptiform discharges significantly reduced compared with before treatment in 41 cases.Conclusion Lamotrigine can significantly improve electroencephalogram changes and epileptiform discharges with partial seizures in children,and lamotrigine can also improve cognitive function in children with epilepsy.
出处
《中国当代医药》
2014年第4期93-94,共2页
China Modern Medicine
基金
内蒙古医科大学科技百万工程(kjbw2012005)
关键词
癫痫
拉莫三嗪
脑电图
Epilepsy
Lamotrigine
Electroencephalogram
