冠心病合并2型糖尿病患者的临床特点分析

Clinical features analysis of patients with coronary artery disease combined with type 2 diabetes

目的探讨冠心病合并2型糖尿病患者的临床特点。方法随机选取本院内科2007年1月～2013年1月收治的冠心病合并糖尿病患者82例作为研究组。同时随机选取90例无合并症的冠心病患者作为对照组。比较两组患者的糖化血红蛋白、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL—C）、低密度脂蛋白胆固醇（LDL—C）水平和急性冠状动脉综合征（ACS）的发生率。结果与对照组比较，研究组的糖化血红蛋白、TG水平和ACS的发生率均显著升高（P〈0．05），而HDL—C水平则显著降低（P〈0．05）；两组患者的LDL—C水平差异无统计学意义（P〉0．05）。研究组患者的ACS发生率为77％．明显高于对照组的59％（P〈0．05）。结论合并糖尿病的冠心病患者更加容易发生血脂代谢障碍，促进了冠心病的发生和发展。

Objective To discuss the clinical features of patients with coronary artery disease combined with type 2 diabetes. Methods 82 cases of patitents with coronary artery disease combined with type 2 diabetes were selected random- ly from Jan. 2007 to Jan. 2013 in department of internal medicine in our hospital as the research group,and 90 cases coronary artery disease patients without diabetes were chosen as control group.The levels of glycosylated hemoglobin,triacyl- glycerol（TG）,high density lipoprotein cholesterol（HDL-C）,low density lipoprotein cholesterin（LDL-C） and the incidence rate of acute coronary syndrome（ACS） were measured between the two groups. Results Compared with the control group, the glycosylated hemoglobin,TG and the incidence rate of ACS in the were research group all increased greatly （P〈0.05）, while the level of HDL-C decreased greatly（P〈0.05）,and the difference of LDL-C between two groups was not statistically significant（P〉0.05）.The incidence rate of ACS in research group was 77%,which was significantly higher than that of control group（59%）（P〈0.05）. Conclusion The patients with coronary artery disease combined with diabetes mellitus are more likely to happen lipid metabolic disorders,which accelerate the happening and development of coronary arteries.