原发性肝脏非霍奇金淋巴瘤1例报告暨文献复习

Primary Hepatic Non-Hodgkin Lymphoma:A Case Report and Associated Literature Review

目的探讨原发性肝脏非霍奇金淋巴瘤的相关诊断与治疗。方法回顾性分析我院近期收治原发性肝脏非霍奇金淋巴瘤1例患者的临床资料,并进行相关文献复习。结果患者在全麻下施行右肝后叶+Ⅸ段切除术,术中见无瘤肝脏质地好,无肝硬化表现,肿物约14 cm×11 cm×9 cm。术后病理检查提示为原发性肝脏非霍奇金淋巴瘤,B细胞来源。术后患者恢复顺利,8 d后拆线,转血液内科行一疗程R-CHOP方案化疗后出院。结论原发性肝脏非霍奇金淋巴瘤罕见且无特异性表现,因此其诊断较为困难,手术为其有效治疗方法,但就现有认识而言,仍需进一步加强相关研究及认识。

Objective To explore the related methods of diagnosis and treatment in primary hepatic non- Hodgkin lymphoma. Methods The clinical data of a patient suffered primary hepatic non-Hodgkin lympho- ma were retrospectively analyzed. And the associated literatures were reviewd. Results The resection of the fight posterior hepatic lobe and segment IX was performed in the patient under general anesthesia. During the operation, the liver with tumor-free showed good texture without cirrhosis. The excisional tumor sized 14 cm× 11 cm×9 cm. The postoperative pathological examination showed primary liver non-Hodgkin lymphoma, B-cell origin. The well recovery was achieved and the stitches were removed 8 days after the operation. A course of R- CHOP chemotherapy was following treatment before discharge from hospital. Conclusions Primary hepatic non-Hodgkin lymphoma is a kind of rare neoplasms without specific performance, so, the diagnosis is very diffi- cult. Surgical intervention is an effective diagnosis and treatment method. The final diagnosis is determined by pathological evidences. But in terms of existing knowledge, the associated awareness of primary hepatic non- Hodgkin lymphoma should be further researched.