MALDI-TOF MS技术在临床病原真菌鉴定中的应用进展

Advances in the application of Matrix-assisted laser desorption ionization time-of-flight mass spectrometry for identification of clinically pathogenic fungi

基质辅助激光解吸电离飞行时间质谱技术(MALDI-TOF-MS)目前是一种快速而可靠的微生物鉴定方法。随着可鉴定真菌谱的完善,MALDI-TOF MS技术已逐步应用于临床常见致病酵母菌、酵母样真菌和丝状菌的鉴定中,本文将就此做一综述。

Matrix-assisted laser desorption ionization-time of flight mass spectrometry （MALDI-TOF MS）-based systems is a rapid and reliable method in identification of microorganism.With the improvement of identifiable fungal species spectrum,the application of MALDI-TOF MS systems have been introduced to identification of clinically pathogenic yeasts,yeast-like fungi,filamentous fungi and dermatophytes.