热毒宁注射液和利巴韦林注射液治疗轮状病毒肠炎的疗效对比

The comparative efficacy of reduning injection and ribavirin injection in the treatment of rotavirus enteritis

目的：探讨热毒宁注射液和利巴韦林注射液治疗轮状病毒肠炎的临床疗效，为临床推广作出指导。方法选择我院自2010年1月～2013年1月收治的轮状病毒肠炎患者152例为研究对象，随机分为两组。对照组给予利巴韦林注射液治疗，观察组则给予热毒宁注射液治疗。对比观察两组患者的临床治疗效果。结果（1）观察组治疗后的临床症状消失时间明显较对照组短，差异具有统计学意义（P＜0.05）；（2）观察组患者治疗后的总有效率为96.05%（73/76），明显高于对照组80.26%（61/76），差异具有统计学意义（P＜0.05）；（3）两组患者治疗后均未发生严重肝、肾功能损害等不良反应，差异无统计学意义（P＞0.05）。结论热毒宁注射液治疗轮状病毒肠炎的临床疗效显著，安全可靠，值得临床广泛推广。

Objective To investigate clinical efficacy of Reduning injection and ribavirin injection in the treatment of rotavirus enteritis,which made guidance for clinical treatment. Methods 152 cases patients admitted to our hospital from January 2010 to January 2013 were divided into control group（given ribavirin injection） and observation group （given Reduning injection） ,the efficacy of two groups were compared. Results （1）After treatment, the clinical symptoms disappeared time was shorter than that of control group,the difference was statistically significant （P0.05）. Conclusion Reduning injection has a significant effect on treating rotavirus enteritis,which was worthy of clinical widely.