诱发电位在功能性肠病研究中的价值

Value of evoked potential in study of functional bowel disorders

近年来,随着神经胃肠病学的发展及神经生理学检查的应用,逐步揭示了胃肠道活动通过各处的传出和传入通路与大脑皮质活动相关联.大脑中枢和胃肠道之间传出及传入神经通路状态与肛门直肠的具体功能密切联系,学者们提出"脑肠轴"、"脑肠互动"解释消化系与中枢神经系统之间的双向作用.诱发电位在诊断及研究神经系统各部位电生理变化方面有重要作用,并为研究脑-肠传导通路提供了具体信息,促进了对脑-肠轴异常相关疾病的诊断和理解,为探索新的治疗方法提供依据.本文在文献研究的基础上,对各种诱发电位技术在功能性肠病研究中的作用作一综述.

In recent years, the development of neurogastroenterology and the application of neurophysiologic examinations have gradually revealed the association of gastrointestinal activity with cortical activity through the efferent and afferent pathways. The state of nerve conduction pathway between the brain and gastrointestinal tract is closely related with specific functions of the anus and rectum. Scholars have put forward the ＂brain gut axis＂ and ＂brain gut interaction＂ theories to explain the bidirectional interaction between the gastrointestinal tract and central nervous system. Evoked potentials have an important role in the diagnosis and research of electrophysiological changes in various parts of the neural system, which provides practical information for the study of the brain-gut pathway, promotes the diagnosis and understanding of diseases related to the brain-gut axis abnormalities, and provides the basis for developing new treatment methods. In this paper, we summarize the roles of various evoked potential techniques in the study of functional bowel disorders.